thyrotropin alpha /-trō′pin/ , a thyroid-stimulating hormone made with recombinant DNA technology. It increases the uptake of radioactive iodine in the thyroid and the secretion of thyroxine by the thyroid. ▪ INDICATIONS: It is prescribed in diagnostic tests and to enhance uptake of 131I in the treatment of thyroid cancer. ▪ CONTRAINDICATIONS: Coronary thrombosis or known hypersensitivity to this drug prohibits its use. It should not be given in untreated Addison’s disease or after myocardial infarction. ▪ ADVERSE EFFECTS: Among the most serious adverse effects are symptoms of hyperthyroidism, allergic reactions, hypotension, and arrhythmias.
