sudorific /so̅o̅′dərif″ik/ [L, sudor, sweat, facere, to make] , 1. adj., pertaining to a substance or condition, such as heat or emotional tension, that promotes sweating. 2. n., a sudorific agent. Sweat glands are stimulated by cholinergic drugs. The alkaloid pilocarpine is a potent sudorific drug, but it is rarely used for that purpose in modern medicine. Also called diaphoretic.