atropine sulfate, an antispasmodic and anticholinergic. ▪ INDICATIONS: It may be prescribed in the treatment of GI hypermotility to decrease the tone of the detrusor muscle of the urinary bladder in urinary tract disorders, for cycloplegic refraction and dilation of the pupil in inflammation of the iris or the uvea, cardiac arrhythmias, and certain kinds of poisoning and as an adjunct to anesthesia. ▪ CONTRAINDICATIONS: GI obstruction, glaucoma, hepatitis, liver or kidney dysfunction, porphyria, or known hypersensitivity to this drug or other anticholinergics prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse reactions are tachycardia, angina, loss of taste, nausea, diarrhea, skin rash, blurred vision, and eye pain. Dry mouth and constipation are common effects.