Smith-Lemli-Opitz syndrome /ō′pitz/ [John Marius Opitz, German-born pediatrician in United States, b. 1935] , an autosomal-dominant syndrome consisting of hypertelorism and hernias and, in males, hypospadias, cryptorchidism, and bifid scrotum. Cardiac anomalies, laryngotracheal malformations, imperforate anus, renal defects, lung hypoplasia, and downslanted palpebral fissures may also be present. Also called G syndrome, hypertelorism-hypospadias syndrome.
