simethicone /simeth′ikōn/ , an antiflatulent that helps the gases to dissolve in liquid by decreasing the surface tension of gas bubbles. ▪ INDICATIONS: It is prescribed to disperse gas pockets in the GI tract. ▪ CONTRAINDICATIONS: There are no significant contraindications other than hypersensitivity to the medication. ▪ ADVERSE EFFECTS: There are no significant adverse effects.