Sevin, a widely used carbamate insecticide known as carbaryl that causes reversible inhibition of cholinesterase. Although less toxic than parathion, carbaryl, when concentrated, may produce skin irritation and systemic poisoning characterized by nausea, vomiting, cramps, diarrhea, diaphoresis, excessive salivation, dyspnea, weakness, loss of coordination, and slurred speech. Large doses may cause coma and death. Carbaryl on the skin is promptly removed by washing with water. Treatment of systemic poisoning includes the immediate IV or intramuscular injection of 1 to 4 mg of atropine sulfate, the administration of artificial respiration and oxygen, gastric lavage, and IV isotonic saline solution to correct dehydration. Brand name for carbaryl.
