scabicide /skab″isīd/ [L, scabere, to scratch, caedere, to kill] , any one of a large group of drugs that destroy the itch mite, Sarcoptes scabiei. These drugs are applied topically in a lotion or cream-based preparation. All are potentially toxic and irritating to the skin. They are used with caution in treating children. Kinds include crotamiton, lindane.