Ruffini’s corpuscles /ro̅o̅fē″nēz/ [Angelo Ruffini, Italian anatomist, 1864–1929] , a variety of oval-shaped, encapsulated nerve endings in the subcutaneous tissue, located principally at the junction of the dermis and the subcutaneous tissue. Ruffini’s corpuscles consist of strong connective tissue sheaths enclosing nerve fibers with many branches that end in small knobs. Compare Golgi-Mazzoni corpuscles, Krause’s corpuscles, Pacini’s corpuscles.
