Rubinstein-Taybi syndrome /ro̅o̅′binstīn tā′bē/ [Jack Herbert Rubinstein, American pediatrician, 1925–2006; Hooshang Taybi, American radiologist, 1919–2006] , a congenital condition characterized by cognitive impairment and motor delays; broad thumbs and great toes; short stature; characteristic facies, including high-arched palate and straight or beaked nose; various eye abnormalities; pulmonary stenosis; keloid formation in surgical scars; large foramen magnum; and abnormalities of the vertebrae and sternum.
