rosuvastatin, an antilipemic. ▪ INDICATIONS: This drug is used as an adjunct in primary hypercholesterolemia (types IIa and IIb), mixed dyslipidemia, elevated serum triglycerides, and homozygous low-density lipoprotein receptor disorder. ▪ CONTRAINDICATIONS: Pregnancy, lactation, active liver disease, and known hypersensitivity to this drug prohibit its use. ▪ ADVERSE EFFECTS: Adverse effects of this drug include vomiting; leg, shoulder, or localized pain; insomnia; paresthesia; photosensitivity; rhinitis; sinusitis; bronchitis; and increased cough. Life-threatening side effects include liver dysfunction, myositis, rhabdomyolysis, thrombocytopenia, hemolytic anemia, and leukopenia. Common side effects include nausea, constipation, abdominal pain, flatus, diarrhea, dyspepsia, heartburn, asthenia, muscle cramps, arthritis, arthralgia, myalgia, headache, dizziness, rash, pruritus, and pharyngitis.
