rosiglitazone, an oral antidiabetic drug. ▪ INDICATIONS: It is used to treat stable type 2 diabetes mellitus. ▪ CONTRAINDICATIONS: Lactation, diabetic ketoacidosis, and known hypersensitivity to thiazolidinediones prohibit its use. It is also contraindicated in children. ▪ ADVERSE EFFECTS: Adverse effects include upper respiratory infection, sinusitis, anemia, back pain, diarrhea, edema, fatigue, headache, and hyperglycemia or hypoglycemia.