rabies vaccine, one of the sterile suspensions of killed rabies virus ▪ INDICATIONS: It is prescribed for immunization and postexposure prophylaxis against rabies. ▪ CONTRAINDICATIONS: A history of allergic reaction to components of the vaccine prohibits its use. Several preparations of the vaccine are available in North America, and contraindications vary among brands. ▪ ADVERSE EFFECTS: Among the most serious adverse effects are severe hypersensitivity reactions. Pain and inflammation at the site of injection were once common but are now rare.