pruritus /pro͝orī″təs/ [L, prurire, to itch] , the symptom of itching, an uncomfortable sensation leading to the urge to scratch. Scratching may result in secondary infection. Some causes of pruritus are allergy, infection, jaundice, chronic renal disease, lymphoma, and skin irritation. Treatment is best directed at the cause. Symptomatic relief may be obtained with antihistamines, starch baths, topical corticosteroids, cool water, or alcohol applications. −pruritic, adj.