promethazine hydrochloride /-meth″əzēn/ , a phenothiazine antiemetic, antihistamine, and sedative. ▪ INDICATIONS: It is prescribed in the treatment of motion sickness, nausea, rhinitis, itching, and skin rash and as an adjunct to anesthesia and pain control. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug or to other phenothiazines or severe central nervous system depression or coma prohibits its use. ▪ ADVERSE EFFECTS: Drowsiness, hypotension, and dry mouth are the most common adverse effects.
