potential abnormality of glucose tolerance

potential abnormality of glucose tolerance, a classification that includes people who have never had abnormal glucose tolerance but who have an increased risk of diabetes or impaired glucose tolerance. Factors associated with an increased risk of type 1 diabetes mellitus include having circulating islet cell antibodies, being a monozygotic twin or sibling of a type 1 diabetes patient, and being the offspring of a type 1 diabetes patient. Factors associated with an increased risk of type 2 diabetes mellitus include being a first-degree relative of a type 2 diabetes patient (particularly in a family in which there are several generations with type 2 diabetes); giving birth to a neonate weighing more than 9 pounds (4.086 kilograms); being a member of a racial or ethnic group with a high prevalence of diabetes, such as some Native American groups; and being an obese adult. Also called potential diabetes. See also diabetes mellitus.