arsenic poisoning, toxic effect caused by the ingestion or inhalation of arsenic or a substance containing arsenic, an ingredient in some pesticides, herbicides, dyes, and medicinal solutions. Small amounts absorbed over a period of time may result in chronic poisoning, producing nausea, headache, coloration and scaling of the skin, hyperkeratoses, anorexia, and white lines across the fingernails. Ingestion of large amounts of arsenic results in severe GI pain, diarrhea, vomiting, and swelling of the extremities. Renal failure and shock may occur, and death may result. Determination of the presence of arsenic in the urine, hair, or fingernails is diagnostic.
