pegaptanib, a miscellaneous ophthalmic agent that binds to vascular endothelial growth factor, thereby inhibiting angiogenesis. ▪ INDICATIONS: This drug is used in the treatment of neovascular age-related macular degeneration. It may be used alone or with photodynamic therapy. ▪ CONTRAINDICATIONS: Ocular or periocular infections and known hypersensitivity to this drug prohibit its use. ▪ ADVERSE EFFECTS: Adverse effects of this drug include retinal detachment and traumatic cataract. Common side effects include anterior chamber inflammation, blurred vision, conjunctival hemorrhage, corneal edema, cataract, eye discharge, eye pain, increased intraocular pressure, punctuate keratitis, reduced visual acuity, vitreous floaters, vitreous opacities, blepharitis, conjunctivitis, and photophobia.
