pediatric dosage, the determination of the correct amount, frequency, and total number of doses of a medication to be administered to a child or infant. Such variables as the age, weight, body surface area, and ability of the child to absorb, metabolize, and excrete the medication must be considered, as well as the expected action of the drug, possible side effects, and potential toxicity. Various formulas have been devised to calculate pediatric dosage from a standard adult dose, although the most reliable method is to use one of the formulas to calculate the proportional amount of body surface area to body weight. See also Clarkâs rule.