pancreatin /pan″krē·ətin′, -krē·ā″tin/ , a concentrate of pancreatic enzymes from swine or beef cattle. ▪ INDICATIONS: It is prescribed as an aid to digestion to replace endogenous pancreatic enzymes in cystic fibrosis and after pancreatectomy. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug or to pork or beef protein, acute pancreatitis, or a flare in chronic pancreatitis prohibits its use. ▪ ADVERSE EFFECTS: There are no known serious adverse effects. High doses may cause nausea or diarrhea.