oxandrolone /oksan″drəlōn/ , an androgen. ▪ INDICATIONS: It is prescribed in the treatment of bone pain accompanying osteoporosis and for the stimulation of weight gain after extensive surgery or trauma or when a pathophysiological reason exists for failure to maintain normal weight. ▪ CONTRAINDICATIONS: Cancer of the male breast or prostate, liver disease, pregnancy or suspected pregnancy, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse reactions are hirsutism, acne, liver toxicity, electrolyte imbalances, and various endocrine effects in some patients.