omalizumab, a monoclonal antibody. ▪ INDICATIONS: This drug is used to treat moderate to severe persistent asthma. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Adverse effects of this drug include earache, dizziness, fatigue, pain, viral infections, sinusitis, upper respiratory infections, pharyngitis, pruritus, dermatitis, injection site reactions, arthralgia, fracture, and leg and arm pain. A life-threatening side effect is malignancy.