olanzapine, an antipsychotic and neuroleptic. ▪ INDICATIONS: It is used to treat psychotic disorders. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Neuroleptic malignant syndrome is a rare but life-threatening effect. Other adverse effects are orthostatic hypotension, tachycardia, chest pain, blurred vision, dry mouth, nausea, vomiting, anorexia, constipation, abdominal pain, weight gain, urinary retention, urinary frequency, enuresis, impotence, amenorrhea, gynecomastia, breast engorgement, premenstrual syndrome, rash, dyspnea, rhinitis, cough, pharyngitis, extrapyramidal symptoms, seizures, headache, fever, insomnia, somnolence, agitation, nervousness, hostility, dizziness, hypertonia, tremor, euphoria, joint pain, and twitching.
