ofloxacin /oflak″səsin/ , a fluoroquinolone antibiotic. ▪ INDICATIONS: It is used to treat lower respiratory tract infections, genitourinary infections, skin and skin structure infections, and conjunctivitis. ▪ CONTRAINDICATIONS: A known hypersensitivity to quinolones prohibits its use. ▪ ADVERSE EFFECTS: Among the most common adverse effects are dizziness, headache, fatigue, somnolence, diarrhea, nausea, and vomiting.