acarbose, an oral alpha glucosidase inhibitor. ▪ INDICATIONS: It is prescribed in the treatment of type 2 diabetes mellitus; it slows the digestion of complex carbohydrates and reduces the demand for insulin. The drug is indicated for use with dietary modifications or other medications that treat diabetes in patients whose hyperglycemia is not sufficiently controlled by diet alone. ▪ CONTRAINDICATIONS: It should not be used by patients with diabetic ketoacidosis or intestinal diseases that may impair digestion or absorption. Caution is advised for use in patients with renal dysfunction. ▪ ADVERSE EFFECTS: The side effects most often reported include flatulence, diarrhea, and abdominal pain. Increased transaminase levels have been reported in patients taking high doses.
