occlusion /əklo̅o̅″zhən/ [L, occludere, to close up] , 1. (in anatomy) a blockage in a canal, vessel, or passage of the body; the state of being closed. 2. (in dentistry) any contact between the incising or masticating surfaces of the maxillary and mandibular teeth. −occlusive, adj., −occlude, v.