nisoldipine, a calcium channel blocker. ▪ INDICATIONS: It causes vasodilation and is prescribed, either alone or in combinations, for the management of hypertension. ▪ CONTRAINDICATIONS: Factors that prohibit its use include hypersensitivity to nisoldipine or other dihydropyridine calcium channel blockers. High-fat meals and grapefruit juice should be avoided because these foods can cause sudden increases in the blood levels of the drug. ▪ ADVERSE EFFECTS: Fluid retention, headache, nausea, dizziness, pharyngitis, shortness of breath, cough, and palpitations are among the more common adverse effects.
