neonatal pustular melanosis, a transient skin condition of the neonate characterized by vesicles present at birth that become pustular. The lesions contain neutrophils rather than eosinophils as seen in erythema toxicum neonatorum. They disappear within 72 hours, leaving dark spots that gradually fade by about 3 months of age. The cause is unknown. The condition is twice as common in black infants as in white infants.