nalidixic acid /nal′idik″sik/ , an antibacterial drug. ▪ INDICATIONS: It is prescribed in the treatment of certain urinary tract infections. ▪ CONTRAINDICATIONS: Renal or hepatic insufficiency, a history of convulsive disorders, or known hypersensitivity to this drug prohibits its use. It should not be used in children less than 3 months of age and should be used with care in prepubertal children. ▪ ADVERSE EFFECTS: Quinolones have caused tendon rupture, especially in prepubertal children, and severe hypersensitivity reactions. Among the more serious effects are increased intracranial pressure, seizures, hemolytic anemia in people affected with glucose-6-phosphate dehydrogenase deficiency, and GI and neurological disturbances.
