myeloma /mī′əlō″mə/ [Gk, myelos + oma, tumor] , an osteolytic neoplasm consisting of a profusion of cells typical of the bone marrow that may develop in many sites and cause extensive destruction of the bone. The tumor occurs most frequently in the ribs, vertebrae, pelvic bones, and flat bones of the skull. Intense pain and spontaneous fractures are common. The tumor is radiosensitive, and local lesions are curable. Kinds include endothelial myeloma, extramedullary myeloma, giant cell myeloma, multiple myeloma, osteogenic myeloma.
