antidiuretic /-dī′əret″ik/ [Gk, anti + dia, through, ourein, to urinate] , 1. pertaining to the suppression of urine formation and/or excretion. 2. an antidiuretic hormone, produced in hypothalamic nuclei and stored in the posterior lobe of the pituitary gland, that suppresses urine formation by permitting the resorption of water-collecting ducts in the kidneys. −antidiuresis, n.