minoxidil /mīnok″sidil/ , a vasodilator. ▪ INDICATIONS: It is prescribed in the treatment of severe refractory hypertension and as a topical solution for the treatment of androgenic alopecia in both males and females. ▪ CONTRAINDICATIONS: Pheochromocytoma, acute myocardial infarctions, dissecting aortic aneurysm, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse effects are tachycardia, pericardial effusion, cardiac tamponade, salt and water retention, and excessive hair growth. GI disturbances also may occur.