milk of magnesia, a laxative and antacid containing magnesium hydroxide. ▪ INDICATIONS: It is prescribed to relieve constipation and, less commonly, acid indigestion. ▪ CONTRAINDICATIONS: Renal impairment, symptoms of appendicitis, or known hypersensitivity to the drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse effects are diarrhea and hypermagnesemia, which usually occur in patients who have impaired renal function.