methsuximide /methsuk″simīd/ , an anticonvulsant drug. ▪ INDICATIONS: It is prescribed in the treatment of refractory absence seizures. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug or to any succinimide prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are blood dyscrasias, liver and kidney damage, and systemic lupus erythematosus.