Melkersson-Rosenthal syndrome

Melkersson-Rosenthal syndrome /mel′kərson rō′zentäl/ [Ernst Gustaf Melkersson, Swedish physician, 1898–1932; Curt Rosenthal, German psychiatrist, 1892-1937] , an autosomal-dominant condition usually beginning in childhood or adolescence, characterized chiefly by chronic noninflammatory facial swelling, localized particularly to the lips, with recurrent facial palsy and sometimes fissured tongue. Associated ophthalmic symptoms include lagophthalmos, blepharochalasis, swollen eyelids, burning sensation of the eyes, corneal opacities, retrobulbar neuritis, and exophthalmos. Also called Melkersson’s syndrome.