megestrol acetate /məjes″trōl/ , an antineoplastic progestational agent. ▪ INDICATIONS: It is prescribed to treat endometrial cancer and more commonly to palliate advanced endometrial and breast cancer. It is also used to stimulate appetite and to promote weight gain in cachexia patients. ▪ CONTRAINDICATIONS: Hypersensitivity to the drug prohibits its use. ▪ ADVERSE EFFECTS: Adverse effects include edema and breakthrough bleeding.
