megakaryocyte /meg′əker″ē·əsīt′/ [Gk, megas, large, karyon, nut, kytos, cell] , bone marrow cell measuring 35 to 160 μm in diameter and having a multilobed nucleus. Megakaryocytes are platelet precursors. Also spelled megacaryocyte. See also platelets. −megakaryocytic, adj.