McArdle’s disease /məkär″dəlz/ [Brian McArdle, English neurologist, 1911–2002] , an inherited glycolic storage disease marked by an absence of myophosphorylase B and abnormally large amounts of glycogen in skeletal muscle. It is milder than other glycogen storage diseases, characterized by muscle fatigability and stiffness after exercise. The only treatment is avoidance of exercise. Also called glycogen storage disease, type V. See also glycogen storage disease.
