Marburg virus disease

Marburg virus disease /mär″bərg/ , a severe febrile viral disease characterized by rash, hepatitis, pancreatitis, and severe GI hemorrhages. The disease is caused by the Marburg virus, a member of the Filoviridae family, which also includes the Ebola virus. An epidemic in Marburg, Germany, in 1967 was apparently caused by infected imported African green monkeys. The disease may be transmitted to hospital personnel by improper handling of contaminated needles or from hemorrhagic lesions of patients. The diagnosis is made through serological abnormalities. There is no effective treatment. Also called hemorrhagic fever. See also Ebola virus disease.