angiogenesis /an′jē·ōjen″əsis/ [Gk, angeion + genesis, origin] , the formation of new blood vessels, a process controlled by chemicals produced in the body that stimulate blood vessels or form new ones. Angiogenesis plays an important role in the growth and spread of cancer. Angiogenesis also occurs in the healthy body for healing of wounds and restoring blood flow to tissues after injury.