levobunolol hydrochloride /-bun″əlol/ , a topical ophthalmic beta-adrenergic blocker drug for glaucoma. ▪ INDICATIONS: It is prescribed for the treatment of chronic open-angle glaucoma and ocular hypertension. ▪ CONTRAINDICATIONS: It is contraindicated for patients with bronchial asthma, severe chronic obstructive pulmonary disease, sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock. ▪ ADVERSE EFFECTS: Adverse effects may include transient ocular burning or stinging, bradycardia, pulmonary edema, and blepharoconjunctivitis.