Leriche’s syndrome /lərēshs″/ [René Leriche, French surgeon, 1879–1955] , a vascular disorder marked by gradual occlusion of the terminal aorta, bilateral iliac arteries, or both; intermittent claudication in the buttocks, thighs, or calves; absence of pulsation in femoral arteries; pallor and coldness of the legs; gangrene of the toes; and, in men, impotence. Symptoms are the result of chronic tissue hypoxia caused by inadequate arterial perfusion of the affected areas. Treatment may include endarterectomy, embolectomy, or synthetic bypass graft at the aortic bifurcation.
