lansoprazole, an antiulcer agent and proton pump inhibitor. ▪ INDICATIONS: It is used to treat gastroesophageal reflux disease (GERD), severe erosive esophagitis, poorly responsive systemic GERD, and pathological hypersecretory conditions (Zollinger-Ellison syndrome, systemic mastocytosis, multiple endocrine adenomas). It is also a potentially effective treatment for duodenal and gastric ulcers and for maintenance of healed duodenal ulcers. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Life-threatening effects are cerebrovascular accident, myocardial infarction, shock, hematuria, and hemolysis. Other adverse effects include confusion, agitation, amnesia, depression, diarrhea, vomiting, nausea, acid regurgitation, anorexia, irritable colon, upper respiratory infections, asthma, bronchitis, dyspnea, alopecia, weight gain or loss, gout, deafness, eye pain, otitis media, chest pain, angina, tachycardia, bradycardia, palpitations, hypertension or hypotension, vasodilation, glycosuria, impotence, kidney calculus, breast enlargement, and anemia.
