isoxsuprine hydrochloride /īsok″səprēn/ , a peripheral vasodilator. ▪ INDICATIONS: It is prescribed for the symptomatic relief of cerebrovascular insufficiency and improvement of circulation in arteriosclerosis, Raynaud’s disease, and Buerger’s disease. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug or arterial bleeding prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are tachycardia, hypotension, chest pain, and dermatitis.