irritant poison [L, irritare, to tease, potio, drink] , any of a large number of toxic substances in the environment that can cause pain in the digestive tract, diarrhea, vomiting, abdominal cramps, and urinary tract disorders. Some irritant chemicals are industrial gases, such as ammonia, chlorine, phosgene, sulfur dioxide, hydrogen sulfide, and nitrogen dioxide, which may leak into the atmosphere.