irbesartan, an antihypertensive drug. ▪ INDICATIONS: It is used to treat hypertension, either alone or in combination with other drugs. It is also used investigationally to treat heart failure and hypertension in patients with diabetic nephropathy caused by type 2 diabetes mellitus. ▪ CONTRAINDICATIONS: Known hypersensitivity and second- and third-trimester pregnancy prohibit its use. ▪ ADVERSE EFFECTS: Anxiety, headache, fatigue, diarrhea, and dyspepsia are among the adverse effects. Common side effects include dizziness, cough, and upper respiratory infection.