intertrigo /in′tərtrī″gō/ [L, inter + terere, to scour] , an erythematous irritation of opposing skin surfaces caused by friction, moisture, warmth, or sweat retention. Common sites are the axillae, the folds beneath large or pendulous breasts, and the inner aspects of the thighs. Maceration and candidal infection may be complications if the area is also warm and moist. Prevention is by weight reduction, powdering, cleansing, and use of antifungal topical medication when necessary. −intertriginous, adj.