insulinoma /in′səlinō″mə/ pl. insulinomas, insulinomata [L, insula + Gk, oma, tumor] , a tumor, usually benign, of the insulin-secreting cells of the islets of Langerhans. Surgical resection of the tumor may be possible, thus limiting the development of hypoglycemia. Also called insuloma, islet cell adenoma. Compare islet cell tumor.