insulin lispro, a pancreatic hormone. ▪ INDICATIONS: It is used to treat ketoacidosis types I and II and types 1 and 2 diabetes mellitus. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug or to protamine prohibits its use. ▪ ADVERSE EFFECTS: Anaphylaxis is a life-threatening effect of this drug. Other adverse effects include blurred vision, dry mouth, flushing, rash, urticaria, warmth, lipohypertrophy, swelling, redness, and rebound hyperglycemia (the Somogyi effect). Lipodystrophy and hypoglycemia are common side effects.