immune gamma globulin, passive immunizing agent obtained from pooled human plasma. Also called immune globulin. See also immunoglobulin G. ▪ INDICATIONS: It is prescribed for immediate short-lived protection against measles, poliomyelitis, chickenpox, serum hepatitis after transfusion, hepatitis A, and other disease-causing organisms to which the person has been recently exposed or may be exposed and as replacement therapy for patients with agammaglobulinemia or hypogammaglobulinemia. ▪ CONTRAINDICATIONS: Known hypersensitivity to gamma globulins prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are pain and inflammation at the site of injection, allergic reactions, and headache.