imipramine hydrochloride /imip″rəmēn/ , a tricyclic antidepressant. ▪ INDICATIONS: It is prescribed in the treatment of mental depression. ▪ CONTRAINDICATIONS: Concomitant administration of monoamine oxidase inhibitors, recent myocardial infarction, cardiovascular disease or seizure disorder, or known hypersensitivity to this drug or to other tricyclic medication prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are sedation, GI disturbances, and cardiovascular and neurological reactions. It should not be withdrawn abruptly. This drug interacts with many other drugs.
